Exaggerated and persistent cutaneous delayed-type hypersensitivity in transgenic mice whose epidermal keratinocytes constitutively express B7-1 antigen.

Since mouse keratinocytes are tolerogenic antigen presenting cells for T cell activation, the expression of second signal molecules such as B7-1 was targeted to epidermal keratinocytes (KC) in vivo in transgenic mice. The expression vector used to create transgenic mice consisted of a keratin 14 pro...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Nasir, A, Ferbel, B, Salminen, W, Barth, R K, Gaspari, A A
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518845/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117411
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