Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells.

Hemodynamic forces induce various functional changes in vascular endothelium, many of which reflect alterations in gene expression. We have recently identified a cis-acting transcriptional regulatory element, the shear stress response element (SSRE), present in the promoters of several genes, that m...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Nagel, T, Resnick, N, Atkinson, W J, Dewey, C F, Gimbrone, M A
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296171/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518844/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117410
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