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Alveolar type II epithelial cells produce interleukin-6 in vitro and in vivo. Regulation by alveolar macrophage secretory products.

The aims of this study were (a) to determine if rat alveolar type II (ATII) cells and human pulmonary epithelial-derived cells (A549 cell line) could generate IL-6 in vitro, (b) to characterize the cytokine regulation of IL-6 gene and protein expression in these cells, and (c) to detect the in vivo...

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Udgivet i:J Clin Invest
Principais autores: Crestani, B, Cornillet, P, Dehoux, M, Rolland, C, Guenounou, M, Aubier, M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296153/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117392
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