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Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy.

Nucleotide excision repair is a DNA repair pathway that is highly conserved in nature, with analogous repair systems described in Escherichia coli, yeast, and mammalian cells. The rate-limiting step, DNA damage recognition and excision, is effected by the protein products of the genes ERCC1 and XPAC...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Dabholkar, M, Vionnet, J, Bostick-Bruton, F, Yu, J J, Reed, E
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296149/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117388
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