Large deletion of the peroxisomal acyl-CoA oxidase gene in pseudoneonatal adrenoleukodystrophy.

We have cloned the cDNA encoding human peroxisomal acyl-CoA oxidase, the first enzyme in the peroxisomal beta-oxidation of very long chain fatty acids. Its nucleotide sequence was found to be highly homologous (85%) to the rat cDNA counterpart. An 88% homology between rat and human was found in the...

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Bibliographic Details
Main Authors: Fournier, B, Saudubray, J M, Benichou, B, Lyonnet, S, Munnich, A, Clevers, H, Poll-The, B T
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC296126/
https://ncbi.nlm.nih.gov/pubmed/8040306
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