Genetic analysis of 29 kindreds with generalized and pituitary resistance to thyroid hormone. Identification of thirteen novel mutations in the thyroid hormone receptor beta gene.

Resistance to thyroid hormone (RTH), with elevated serum free thyroid hormones and nonsuppressed thyrotropin levels, is either relatively asymptomatic, suggesting a generalized disorder (GRTH) or associated with thyrotoxic features, indicating possible selective pituitary resistance (PRTH). 20 GRTH...

Volledige beschrijving

Bibliografische gegevens

Gepubliceerd in:	J Clin Invest
Hoofdauteurs:	Adams, M, Matthews, C, Collingwood, T N, Tone, Y, Beck-Peccoz, P, Chatterjee, K K
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Clinical Investigation 1994
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117362
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!