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Trichodermin (4β-acet­oxy-12,13-epoxy­trichothec-9-ene)

In the title natural product, C(17)H(24)O(4), which is a very potent inhibitor of protein synthesis in mammalian cells, the five-membered ring displays an envelope conformation, whereas the two six-membered rings show different conformations, viz. chair and half-chair.

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Bibliographic Details
Main Authors: Chen, Shao-Yuan, Zhang, Chu-Long, Chen, Yu-Zhe, Lin, Fu-Cheng
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2960951/
https://ncbi.nlm.nih.gov/pubmed/21202093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1600536808006168
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