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Alpha Interferon Inhibits Human T-Cell Leukemia Virus Type 1 Assembly by Preventing Gag Interaction with Rafts

Alpha-2a interferon (IFN-α2a) has beneficial clinical effects on human T-cell leukemia virus type 1 (HTLV-1) infection, but its antiviral mechanism of action is unknown. Antiviral effects of IFN-α2a were studied in 293T cells expressing HTLV-1 proviral DNA and in HTLV-1-infected cells (HOS/PL, MT2,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Feng, Xuan, Vander Heyden, Nancy, Ratner, Lee
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC296084/
https://ncbi.nlm.nih.gov/pubmed/14645593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13389-13395.2003
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