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7-Chloro-11a-phenyl-2,3,5,10,11,11a-hexa­hydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11-dione

The title compound, C(18)H(15)ClN(2)O(2), is a potential human immunodeficiency virus type-1 (HIV-1) non-nucleoside reverse transcriptase inhibitor. The pyrrolidine ring adopts an envelope and the diazepine ring a boat conformation. In the crystal structure, two isomers (R and S) form centrosymmetri...

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Détails bibliographiques
Auteurs principaux: Tamazyan, Rafael, Ayvazyan, Armen, Martirosyan, Ashot, Harutyunyan, Gohar, Martirosyan, Vahan
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2960833/
https://ncbi.nlm.nih.gov/pubmed/21201925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S160053680800408X
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