Protection against Murine Leukemia Virus-Induced Spongiform Myeloencephalopathy in Mice Overexpressing Bcl-2 but Not in Mice Deficient for Interleukin-6, Inducible Nitric Oxide Synthetase, ICE, Fas, Fas Ligand, or TNF-R1 Genes

Some murine leukemia viruses (MuLVs), among them Cas-Br-E and ts-1 MuLVs, are neurovirulent, inducing spongiform myeloencephalopathy and hind limb paralysis in susceptible mice. It has been shown that the env gene of these viruses harbors the determinant of neurovirulence. It appears that neuronal l...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Jolicoeur, Paul, Hu, Chunyan, Mak, Tak W., Martinou, Jean-Claude, Kay, Denis G.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Assuntos:	Pathogenesis and Immunity
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296073/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645573/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.24.13161-13170.2003
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