Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors.

We examined the relative effects of thyrotropin (TSH) and TSH receptor autoantibodies in the sera of patients with autoimmune thyroid disease on three TSH-lutropin/chorionic gonadotropin (LH/CG) receptor extracellular domain chimeras. Each chimera binds TSH with high affinity. Only the chimera with...

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Main Authors: Nagayama, Y, Wadsworth, H L, Russo, D, Chazenbalk, G D, Rapoport, B
格式: Artigo
語言:Inglês
出版: 1991
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC296038/
https://ncbi.nlm.nih.gov/pubmed/1711544
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