Hypoxia and glucose independently regulate the beta-adrenergic receptor-adenylate cyclase system in cardiac myocytes.

We explored the effects of two components of ischemia, hypoxia and glucose deprivation, on the beta-adrenergic receptor (beta AR)-adenylate cyclase system in a model of hypoxic injury in cultured neonatal rat ventricular myocytes. After 2 h of hypoxia in the presence of 5 mM glucose, cell surface be...

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Pubblicato in:	J Clin Invest
Autori principali:	Rocha-Singh, K J, Honbo, N Y, Karliner, J S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296021/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1647415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115279
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