Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptor.

Interleukin-6 is an essential mediator of the bone loss caused by loss of estrogens. Because loss of androgens also causes bone loss, we have examined whether the IL-6 gene is regulated by androgens, and whether IL-6 plays a role in the bone loss caused by androgen deficiency. Both testosterone and...

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Autors principals: Bellido, T, Jilka, R L, Boyce, B F, Girasole, G, Broxmeyer, H, Dalrymple, S A, Murray, R, Manolagas, S C
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC295976/
https://ncbi.nlm.nih.gov/pubmed/7769130
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