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Anti sense DNA down-regulates proteins kinase C-epsilon and enhances vasopressin-stimulated Na+ absorption in rabbit cortical collecting duct.

Hormonal activation of protein kinase C (PKC) is a major signaling mechanism regulating salt and water transport in the distal nephron. We used antisense DNA to down-regulate a PKC isoform in the rabbit cortical collecting duct (CCD) and examined its role in mediating arginine vasopressin's (AVP) ef...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: DeCoy, D L, Snapper, J R, Breyer, M D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295959/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769115/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117978
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