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Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation.

Excess vascular oxidative stress and the local formation of oxidized LDL (ox-LDL) have been implicated in the development of impaired endothelium-dependent arterial relaxation in hypercholesterolemia and atherosclerosis. Dietary antioxidants limit LDL oxidation in vitro and treatment of cholesterol-...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Keaney, J F, Xu, A, Cunningham, D, Jackson, T, Frei, B, Vita, J A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295934/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7769097/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117953
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