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Targeting the Extracellular Membrane-Proximal Domain of Membrane-Bound IgE by Passive Immunization Blocks IgE Synthesis In Vivo

The classical allergic reaction starts seconds or minutes after Ag contact and is committed by Abs produced by a special subset of B lymphocytes. These Abs belong to the IgE subclass and are responsible for Type I hyperreactivity reactions. Treatment of allergic diseases with humanized anti-IgE Abs...

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Autors principals: Feichtner, Stefan, Inführ, Daniela, Achatz-Straussberger, Gertrude, Schmid, Doris, Karnowski, Alexander, Lamers, Marinus, Rhyner, Claudio, Crameri, Reto, Achatz, Gernot
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959155/
https://ncbi.nlm.nih.gov/pubmed/18390733
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