Viricidal effect of polymorphonuclear leukocytes on human immunodeficiency virus-1. Role of the myeloperoxidase system.

Myeloperoxidase (MPO), H2O2, and chloride form an antimicrobial system in neutrophilic polymorphonuclear leukocytes (PMN) effective against a variety of microorganisms. Normal human PMN, when stimulated with phorbol myristate acetate or opsonized zymosan, are viricidal to HIV-1. The viricidal effect...

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Pubblicato in:	J Clin Invest
Autori principali:	Klebanoff, S J, Coombs, R W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1318327/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115810
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