Genome profiling of ERBB2-amplified breast cancers

BACKGROUND: Around 20% of breast cancers (BC) show ERBB2 gene amplification and overexpression of the ERBB2 tyrosine kinase receptor. They are associated with a poor prognosis but can benefit from targeted therapy. A better knowledge of these BCs, genomically and biologically heterogeneous, may help...

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Autori principali: Sircoulomb, Fabrice, Bekhouche, Ismahane, Finetti, Pascal, Adélaïde, José, Hamida, Azza Ben, Bonansea, Julien, Raynaud, Stéphane, Innocenti, Charlène, Charafe-Jauffret, Emmanuelle, Tarpin, Carole, Ayed, Farhat Ben, Viens, Patrice, Jacquemier, Jocelyne, Bertucci, François, Birnbaum, Daniel, Chaffanet, Max
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958950/
https://ncbi.nlm.nih.gov/pubmed/20932292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-539
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