Pharmacokinetic comparability of Prolastin(®)-C to Prolastin(® )in alpha(1)-antitrypsin deficiency: a randomized study

BACKGROUND: Alpha(1)-antitrypsin (AAT) deficiency is characterized by low blood levels of alpha(1)-proteinase inhibitor (alpha(1)-PI) and may lead to emphysema. Alpha(1)-PI protects pulmonary tissue from damage caused by the action of proteolytic enzymes. Augmentation therapy with Prolastin(® )(Alph...

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Main Authors: Stocks, James M, Brantly, Mark L, Wang-Smith, Laurene, Campos, Michael A, Chapman, Kenneth R, Kueppers, Friedrich, Sandhaus, Robert A, Strange, Charlie, Turino, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958874/
https://ncbi.nlm.nih.gov/pubmed/20920295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-10-13
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