Evaluation of Allelic Expression of Imprinted Genes in Adult Human Blood

BACKGROUND: Imprinted genes are expressed from only one allele in a parent-of-origin dependent manner. Loss of imprinted (LOI) expression can result in a variety of human disorders and is frequently reported in cancer. Biallelic expression of imprinted genes in adult blood has been suggested as a us...

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Bibliographic Details
Main Authors: Frost, Jennifer M., Monk, Dave, Stojilkovic-Mikic, Taita, Woodfine, Kathryn, Chitty, Lyn S., Murrell, Adele, Stanier, Philip, Moore, Gudrun E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958851/
https://ncbi.nlm.nih.gov/pubmed/21042416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013556
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