The PTPN22 Locus and Rheumatoid Arthritis: No Evidence for an Effect on Risk Independent of Arg620Trp

OBJECTIVES: The Trp(620) allotype of PTPN22 confers susceptibility to rheumatoid arthritis (RA) and certain other classical autoimmune diseases. There has been a report of other variants within the PTPN22 locus that alter risk of RA; protective haplotype ‘5’, haplotype group ‘6–10’ and susceptibilit...

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Main Authors: Wan Taib, Wan R., Smyth, Deborah J., Merriman, Marilyn E., Dalbeth, Nicola, Gow, Peter J., Harrison, Andrew A., Highton, John, Jones, Peter B. B., Stamp, Lisa, Steer, Sophia, Todd, John A., Merriman, Tony R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958827/
https://ncbi.nlm.nih.gov/pubmed/20975833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013544
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