Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin.

Psoriasis is a hyperproliferative cutaneous disease of unknown etiology and etiopathogenesis. Alteration of keratinocyte adhesiveness to basal lamina has been proposed as the initial disturbance leading to poorly controlled proliferation. Keratinocyte adhesion to basal lamina and lateral interaction...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Pellegrini, G, De Luca, M, Orecchia, G, Balzac, F, Cremona, O, Savoia, P, Cancedda, R, Marchisio, P C
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1992
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295876/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1534817/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115782
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