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Metric learning for enzyme active-site search

Motivation: Finding functionally analogous enzymes based on the local structures of active sites is an important problem. Conventional methods use templates of local structures to search for analogous sites, but their performance depends on the selection of atoms for inclusion in the templates. Resu...

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Détails bibliographiques
Auteurs principaux: Kato, Tsuyoshi, Nagano, Nozomi
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958746/
https://ncbi.nlm.nih.gov/pubmed/20870642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq519
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