Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.

Obesity is frequently associated with insulin resistance and abnormal glucose homeostasis. Recent studies in animal models have indicated that TNF-alpha plays an important role in mediating the insulin resistance of obesity through its overexpression in fat tissue. However, the mechanisms linking ob...

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Библиографические подробности
Главные авторы: Hotamisligil, G S, Arner, P, Caro, J F, Atkinson, R L, Spiegelman, B M
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC295872/
https://ncbi.nlm.nih.gov/pubmed/7738205
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