Honokiol inhibits gastric tumourigenesis by activation of 15-lipoxygenase-1 and consequent inhibition of peroxisome proliferator-activated receptor-γ and COX-2-dependent signals

BACKGROUND AND PURPOSE: Peroxisome proliferator-activated receptor-γ (PPAR-γ), COX-2 and 15-lipoxygenase (LOX)-1 have been shown to be involved in tumour growth. However, the roles of PPAR-γ, COX-2 or 15-LOX-1 in gastric tumourigenesis remain unclear. Here, we investigate the role of 15-LOX-1 induct...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Shing Hwa, Shen, Chin Chang, Yi, Yu Chiao, Tsai, Jaw Ji, Wang, Chih Chien, Chueh, Ju Ting, Lin, Keh Liang, Lee, Tso Ching, Pan, Hung Chuan, Sheu, Meei Ling
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2010
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958642/
https://ncbi.nlm.nih.gov/pubmed/20649594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00804.x
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