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Understanding the effect of mean pore size on cell activity in collagen-glycosaminoglycan scaffolds

Mean pore size is an essential aspect of scaffolds for tissue-engineering. If pores are too small cells cannot migrate in towards the center of the construct limiting the diffusion of nutrients and removal of waste products. Conversely, if pores are too large there is a decrease in specific surface...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Murphy, Ciara M, O'Brien, Fergal J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958613/
https://ncbi.nlm.nih.gov/pubmed/20421733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.4.3.11747
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