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A comparison of human and macaque (Macaca mulatta) immunoglobulin germline V regions and its implications for antibody engineering

Seventy-five V regions encoded by the sequenced genome of one Macaca mulatta specimen have been identified by homology and paired with similar human counterparts. When the human V region of each pair presented no allelic polymorphism, it was directly compared with its homolog. This was the case for...

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Detalhes bibliográficos
Main Authors: Thullier, Philippe, Chahboun, Siham, Pelat, Thibaut
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958574/
https://ncbi.nlm.nih.gov/pubmed/20562531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.2.5.12545
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