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The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent manner

The mechanisms by which epithelial cells regulate the presence of microvilli on their apical surface are largely unknown. A potential regulator is EBP50/NHERF1 (ERM-binding phosphoprotein of 50 kD/Na(+)-H(+) exchanger regulatory factor), a microvillar scaffolding protein with two PDZ domains followe...

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Autori principali: Garbett, Damien, LaLonde, David P., Bretscher, Anthony
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958488/
https://ncbi.nlm.nih.gov/pubmed/20937695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004115
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