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RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network
The Fanconi anemia (FA) network is important for the repair of interstrand DNA cross-links. A key event in FA pathway activation is the monoubiquitylation of the FA complementation group I (FANCI)–FANCD2 (ID) complex by FA complementation group L (FANCL), an E3 ubiquitin ligase. In this study, we sh...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2958487/ https://ncbi.nlm.nih.gov/pubmed/20937699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201005101 |
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