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RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network

The Fanconi anemia (FA) network is important for the repair of interstrand DNA cross-links. A key event in FA pathway activation is the monoubiquitylation of the FA complementation group I (FANCI)–FANCD2 (ID) complex by FA complementation group L (FANCL), an E3 ubiquitin ligase. In this study, we sh...

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Bibliografiske detaljer
Main Authors: Geng, Liyi, Huntoon, Catherine J., Karnitz, Larry M.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958487/
https://ncbi.nlm.nih.gov/pubmed/20937699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201005101
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