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Polyol Formation in Cell Lines of Rat Retinal Capillary Pericytes and Endothelial Cells (TR-rPCT and TR-iBRB)

PURPOSE: The two most widely investigated animal models for diabetic retinopathy (DR) are the rat and dog. In dogs, aldose reductase (AR) is present only in retinal capillary pericytes and their destruction has been linked to polyol accumulation and resulting apoptosis. Since both rat capillary peri...

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Detalhes bibliográficos
Main Authors: Kador, Peter F., Randazzo, James, Blessing, Karen, Makita, Jun, Zhang, Peng, Yu, Kuang, Hosoya, Ken-Ichi, Terasaki, T.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958435/
https://ncbi.nlm.nih.gov/pubmed/19450153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2008.0070
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