Disappearance of cyclin A correlates with permanent withdrawal of cardiomyocytes from the cell cycle in human and rat hearts.

The regulated expression of cyclins controls the cell cycle. Because cardiomyocytes in adult mammals withdraw permanently from the cell cycle and thus cannot regenerate after injury, we examined cyclin expression during development by comparing cyclin A-E mRNA levels in fetal and adult human hearts....

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Yoshizumi, M, Lee, W S, Hsieh, C M, Tsai, J C, Li, J, Perrella, M A, Patterson, C, Endege, W O, Schlegel, R, Lee, M E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7738192/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117918
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