1,25-Dihydroxyvitamin D3 and 12-O-tetradecanoyl phorbol 13-acetate cause differential activation of Ca(2+)-dependent and Ca(2+)-independent isoforms of protein kinase C in rat colonocytes.

Considerable evidence that alterations in protein kinase C (PKC) are intimately involved in important physiologic and pathologic processes in many cells, including colonic epithelial cells, has accumulated. In this regard, phorbol esters, a class of potent PKC activators, have been found to induce a...

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Detalhes bibliográficos
Main Authors: Bissonnette, M, Wali, R K, Hartmann, S C, Niedziela, S M, Roy, H K, Tien, X Y, Sitrin, M D, Brasitus, T A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295833/
https://ncbi.nlm.nih.gov/pubmed/7738187
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