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Triclosan inhibition of mycobacterial InhA in Saccharomyces cerevisiae: yeast mitochondria as a novel platform for in vivo antimycolate assays
AIMS: To demonstrate the suitability of yeast to act as a novel biotechnological platform for conducting in vivo inhibition assays using drugs with low efficacies towards their mycobacterial targets, such as occurs in the situation with triclosan and InhA. METHODS AND RESULTS: A surrogate yeast host...
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| 第一著者: | |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2958301/ https://ncbi.nlm.nih.gov/pubmed/20158608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1472-765X.2010.02812.x |
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