All-trans retinoic acid modulates the retinoic acid receptor-alpha in promyelocytic cells.

We have recently demonstrated that all-trans retinoic acid (RA), the active metabolite of vitamin A, is an efficient alternative to chemotherapy in the treatment of acute promyelocytic leukemia (AML3). We have further shown that, in these AML3 cells, the gene of the retinoic acid receptor-alpha (RAR...

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Détails bibliographiques
Auteurs principaux: Chomienne, C, Balitrand, N, Ballerini, P, Castaigne, S, de Thé, H, Degos, L
Format: Artigo
Langue:Inglês
Publié: 1991
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC295826/
https://ncbi.nlm.nih.gov/pubmed/1661301
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