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Genes within the MHC region have a dramatic influence on radiation-enhanced atherosclerosis in mice
BACKGROUND: C3H/HeJ (C3H) mice develop much smaller atherosclerotic lesions than C57BL/6 (B6) mice when deficient in apolipoprotein E (apoE(−/−)) or fed an atherogenic diet. The two strains differ in H2 haplotypes with B6 having H2(b) and C3H having H2(k). C3.SW-H2(b)/SnJ (C3.SW) is a congenic strai...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2958254/ https://ncbi.nlm.nih.gov/pubmed/20729504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.110.957449 |
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