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Interferon-Alpha Mediates Restriction of Human Immunodeficiency Virus Type-1 Replication in Primary Human Macrophages at an Early Stage of Replication

Type I interferons (IFNα and β) are induced directly in response to viral infection, resulting in an antiviral state for the cell. In vitro studies have shown that IFNα is a potent inhibitor of viral replication; however, its role in HIV-1 infection is incompletely understood. In this study we descr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cheney, Kelly M., McKnight, Áine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958147/
https://ncbi.nlm.nih.gov/pubmed/20975956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013521
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