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Local Induction of Immunosuppressive CD8(+) T Cells in the Gut-Associated Lymphoid Tissues

BACKGROUND: In contrast to intestinal CD4(+) regulatory T cells (T(regs)), the generation and function of immunomodulatory intestinal CD8(+) T cells is less well defined. To dissect the immunologic mechanisms of CD8(+) T cell function in the mucosa, reactivity against hemagglutinin (HA) expressed in...

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Detalhes bibliográficos
Main Authors: Fleissner, Diana, Hansen, Wiebke, Geffers, Robert, Buer, Jan, Westendorf, Astrid M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958146/
https://ncbi.nlm.nih.gov/pubmed/20975955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015373
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