Complement Factor H-Related Proteins CFHR2 and CFHR5 Represent Novel Ligands for the Infection-Associated CRASP Proteins of Borrelia burgdorferi

BACKGROUND: One virulence property of Borrelia burgdorferi is its resistance to innate immunity, in particular to complement-mediated killing. Serum-resistant B. burgdorferi express up to five distinct complement regulator-acquiring surface proteins (CRASP) which interact with complement regulator f...

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Main Authors: Siegel, Corinna, Hallström, Teresia, Skerka, Christine, Eberhardt, Hannes, Uzonyi, Barbara, Beckhaus, Tobias, Karas, Michael, Wallich, Reinhard, Stevenson, Brian, Zipfel, Peter F., Kraiczy, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958145/
https://ncbi.nlm.nih.gov/pubmed/20975954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013519
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