Intertwining Threshold Settings, Biological Data and Database Knowledge to Optimize the Selection of Differentially Expressed Genes from Microarray

BACKGROUND: Many tools used to analyze microarrays in different conditions have been described. However, the integration of deregulated genes within coherent metabolic pathways is lacking. Currently no objective selection criterion based on biological functions exists to determine a threshold demons...

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Main Authors: Chuchana, Paul, Holzmuller, Philippe, Vezilier, Frederic, Berthier, David, Chantal, Isabelle, Severac, Dany, Lemesre, Jean Loup, Cuny, Gerard, Nirdé, Philippe, Bucheton, Bruno
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958130/
https://ncbi.nlm.nih.gov/pubmed/20976008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013518
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