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Comparison of alendronate and sodium fluoride effects on cancellous and cortical bone in minipigs. A one-year study.

Fluoride stimulates trabecular bone formation, whereas bisphosphonates reduce bone resorption and turnover. Fracture prevention has not been convincingly demonstrated for either treatment so far. We compared the effects of 1-yr treatment of 9-mo-old minipigs with sodium fluoride (NaF, 2 mg/kg/d p.o....

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Detalhes bibliográficos
Main Authors: Lafage, M H, Balena, R, Battle, M A, Shea, M, Seedor, J G, Klein, H, Hayes, W C, Rodan, G A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295812/
https://ncbi.nlm.nih.gov/pubmed/7738180
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