Chronic Hypoxia Impairs Muscle Function in the Drosophila Model of Duchenne's Muscular Dystrophy (DMD)

Duchenne's muscular dystrophy (DMD) is a severe progressive myopathy caused by mutations in the DMD gene leading to a deficiency of the dystrophin protein. Due to ongoing muscle necrosis in respiratory muscles late-stage DMD is associated with respiratory insufficiency and chronic hypoxia (CH)....

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Bibliographic Details
Main Authors: Mosqueira, Matias, Willmann, Gabriel, Ruohola-Baker, Hannele, Khurana, Tejvir S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958114/
https://ncbi.nlm.nih.gov/pubmed/20975992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013450
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