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Phospholipase D Promotes Lipid Microdomain-Associated Signaling Events in Mast Cells
Initial IgE-dependent signaling events are associated with detergent-resistant membrane microdomains. Following Ag stimulation, the IgE-receptor (FcεRI) accumulates within these domains. This facilitates the phosphorylation of FcεRI subunits by the Src kinase, Lyn, and the interaction with adaptor p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2958085/ https://ncbi.nlm.nih.gov/pubmed/19794068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802728 |
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