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Targeting the Vasoprotective Axis of the Renin-Angiotensin System: A Novel Strategic Approach to Pulmonary Hypertensive Therapy

A decade has passed since the discovery of angiotensin-converting enzyme 2 (ACE2), a component of the ACE2–angiotensin (Ang)-(1-7)–Mas counterregulatory axis of the renin angiotensin system (RAS). ACE2 is considered an endogenous regulator of the vasoconstrictive, proliferative, fibrotic, and proinf...

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Autors principals: Bradford, Chastity N., Ely, Debra R., Raizada, Mohan K.
Format: Artigo
Idioma:Inglês
Publicat: Current Science Inc. 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957877/
https://ncbi.nlm.nih.gov/pubmed/20556668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11906-010-0122-6
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