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The interface between biomarker discovery and clinical validation: The tar pit of the protein biomarker pipeline

The application of “omics” technologies to biological samples generates hundreds to thousands of biomarker candidates; however, a discouragingly small number make it through the pipeline to clinical use. This is in large part due to the incredible mismatch between the large numbers of biomarker cand...

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Bibliographic Details
Main Authors: Paulovich, Amanda G., Whiteaker, Jeffrey R., Hoofnagle, Andrew N., Wang, Pei
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957839/
https://ncbi.nlm.nih.gov/pubmed/20976028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.200780174
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