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HBx-induced reactive oxygen species activates hepatocellular carcinogenesis via dysregulation of PTEN/Akt pathway

AIM: To investigate the role of hepatitis B virus X-protein (HBx)-induced reactive oxygen species (ROS) on liver carcinogenesis in HBx transgenic mice and HepG2-HBx cells. METHODS: Cell growth rate was analyzed, and through western blotting, mitogenic signaling was observed. Endogenous ROS from wild...

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Detalles Bibliográficos
Main Authors: Ha, Hye-Lin, Yu, Dae-Yeul
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957601/
https://ncbi.nlm.nih.gov/pubmed/20954279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i39.4932
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