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Human Immune-reactivity against Liver Sinusoidal Endothelial Cells from GalTα(1,3)GalT-Deficient Pigs
BACKGROUND: Elimination of galactose-α(1,3)galactose (Gal) expression in pig organs has been previously shown to prevent hyperacute xenograft rejection. However, naturally present antibodies to non-Gal epitopes activate endothelial cells leading to acute humoral xenograft rejection. Still, it is unk...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2957548/ https://ncbi.nlm.nih.gov/pubmed/20573304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368910X508898 |
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