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TESTOSTERONE-DOWNREGULATED AKT PATHWAY DURING CARDIAC ISCHEMIA/REPERFUSION: A MECHANISM INVOLVING BAD, BCL-2 AND FOXO3A
BACKGROUND: Lower levels of myocardial Akt activity in males are associated with a higher incidence of heart failure and worsened cardiac function after ischemia/reperfusion (I/R). While Akt activation by estrogen provides cardioprotection in females, no information exists regarding the effect of te...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2957547/ https://ncbi.nlm.nih.gov/pubmed/20850791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2010.07.041 |
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