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TESTOSTERONE-DOWNREGULATED AKT PATHWAY DURING CARDIAC ISCHEMIA/REPERFUSION: A MECHANISM INVOLVING BAD, BCL-2 AND FOXO3A

BACKGROUND: Lower levels of myocardial Akt activity in males are associated with a higher incidence of heart failure and worsened cardiac function after ischemia/reperfusion (I/R). While Akt activation by estrogen provides cardioprotection in females, no information exists regarding the effect of te...

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Detalhes bibliográficos
Main Authors: Huang, Chunyan, Gu, Hongmei, Zhang, Wenjun, Herrmann, Jeremy L., Wang, Meijing
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957547/
https://ncbi.nlm.nih.gov/pubmed/20850791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2010.07.041
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