High-precision recording of the action potential in isolated cardiomyocytes using the near-infrared fluorescent dye di-4-ANBDQBS

The use of voltage-sensitive fluorescent dyes (VSD) for noninvasive measurement of the action potential (AP) in isolated cells has been hindered by low-photon yield of the preparation, dye toxicity, and photodynamic damage. Here we used a new red-shifted VSD, di-4-ANBDQBS, and a fast electron-multip...

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Autori principali: Warren, Mark, Spitzer, Kenneth W., Steadman, Bruce W., Rees, Tyler D., Venable, Paul, Taylor, Tyson, Shibayama, Junko, Yan, Ping, Wuskell, Joseph P., Loew, Leslie M., Zaitsev, Alexey V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
Soggetti:
Innovative Methodology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957348/
https://ncbi.nlm.nih.gov/pubmed/20601458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00248.2010
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