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Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries

The goals of this study were to 1) determine the acute effect of ANG-(1-7) on vascular tone in isolated middle cerebral arteries (MCAs) from Sprague-Dawley rats fed a normal salt (NS; 0.4% NaCl) diet, 2) evaluate the ability of chronic intravenous infusion of ANG-(1-7) (4 ng·kg(−1)·min(−1)) for 3 da...

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Autori principali: Durand, Matthew J., Raffai, Gábor, Weinberg, Brian D., Lombard, Julian H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957344/
https://ncbi.nlm.nih.gov/pubmed/20656887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00328.2010
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