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Insulin- and leptin-regulated fatty acid uptake plays a key causal role in hepatic steatosis in mice with intact leptin signaling but not in ob/ob or db/db mice

Hepatic steatosis results from several processes. To assess their relative roles, hepatocellular long-chain fatty acid (LCFA) uptake was assayed in hepatocytes from C57BL/6J control mice, mice with steatosis from a high-fat diet (HFD) or 10%, 14%, or 18% ethanol (EtOH) in drinking water [functioning...

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Detalhes bibliográficos
Main Authors: Ge, Fengxia, Zhou, Shengli, Hu, Chunguang, Lobdell, Harrison, Berk, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957339/
https://ncbi.nlm.nih.gov/pubmed/20595619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00434.2009
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